Research into MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is at the forefront of metabolic and longevity science. As a 16-amino-acid peptide encoded within the mitochondrial genome, MOTS-c acts as a critical signaling molecule that regulates metabolic homeostasis and cellular energy across the entire system.
Key Benefits
MOTS-c is a primary subject for researchers investigating the intersection of mitochondrial function and physical performance:
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Metabolic Regulation: Studied for its role in enhancing glucose metabolism and improving insulin sensitivity.
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Exercise Mimetic: Known to activate the AMPK pathway, potentially simulating the physiological benefits of physical exercise at a cellular level.
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Mitochondrial Proteostasis: May promote the survival of cells under metabolic stress by maintaining mitochondrial integrity.
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Longevity & Anti-Aging: Research explores its capacity to combat age-related metabolic decline and increase physical lifespan in model organisms.
Research Applications
Due to its unique origin in the mitochondria, MOTS-c provides a versatile platform for numerous specialized research fields:
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Metabolic Syndrome & Obesity: Investigate its efficacy in preventing weight gain and regulating lipid metabolism.
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Skeletal Muscle Health: Study its impact on muscle fiber composition and its potential to prevent sarcopenia (age-related muscle loss).
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Endurance & Performance: Explore how it modulates energy expenditure and systemic stamina during high-intensity stress.
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Cardiovascular Health: Examine its role in protecting vascular function and reducing inflammation within the circulatory system.
Storage & Handling
To maintain the structural integrity and potency of MOTS-c, store the lyophilized peptide in a cool, dry environment, preferably below 25°C. For extended preservation, storage at -20°C is highly recommended. Once reconstituted, the solution must be stored in a refrigerator at 2-8°C and should be used within a controlled timeframe to ensure peak biological activity.
Disclaimer: MOTS-c is offered for research purposes only. This product is not intended for human consumption or therapeutic use. It is essential to follow all appropriate laboratory safety and handling procedures when conducting research with this peptide.
At Peptides Canada, we specialize in providing research professionals with reliable, high-purity peptides Made in Canada. Our commitment to excellence ensures that your exploration into metabolism, longevity, and mitochondrial health is supported by the finest materials available.

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